Senior Bioinformatician | Wellcome Trust Sanger Institute

Senior Bioinformatician | Wellcome Trust Sanger Institute

  • Grade: 2
  • Salary per annum: £37,865-£45,359
  • Full Time or Part Time: Full Time
  • Contract Type: Maternity Cover
  • Contract Length: 9 months
  • Job Reference84149

We seek a talented and highly motivated Bioinformatician to play a crucial role in expanding and developing the new resource on cancer mutations at the Wellcome Sanger Institute within the COSMIC group.

The Opportunity

We have started a new project, the Cancer Mutation Census, aiming to characterise every somatic mutation in every form of cancer, to define – at high-resolution across global populations – the important events which are driving disease. Having the first version of Cancer Mutation Census released, we would like you to help us expanding and improving this resource by bringing additional annotations, refining the scoring system, and more deeply integrating it with other resources developed in COSMIC. You will have the opportunity to have a unique impact on beating cancer by improving a resource that helps scientists across the world to better understand the biology of the disease and identify new diagnostic and therapeutic opportunities.

About you

You will work together with COSMIC science team, bringing bioinformatic expertise to this project. The resources of COSMIC, the world’s largest and most detailed database of cancer mutations will be available to you, including unlimited access to HPC facilities. Within the Sanger Institute, you will have also access to global specialists in genomics with decades of experience discovering new disease genes, who are already exploring these data.

About us:

COSMIC

A revolution is underway in health informatics, with genetics increasingly important in understanding human health and disease. COSMIC is a database of genetic mutations in cancer, is a major resource in cancer research, used by over 4000 scientists every day across the informatics, diagnostic and pharmaceutical industries. We are expanding rapidly and developing a range of new services to support multiple academic and industrial research efforts.

Essential Skills

Technical Skills:

  • MSc in Bioinformatic or Computer Science discipline or equivalent experience
  • Experience in integrating and annotating large genomic datasets from multiple sources, especially in variant annotation and integration
  • Substantial knowledge of relational databases
  • Substantial knowledge of at least one programming language
  • Experience with reading and developing legacy code

Behavioural Competencies:

  • Self-motivated, able to work independently and organise own workload
  • Demonstrated ability to independently run data science project
  • Excellent communication and effective team-working skills

Ideal Skills

  • Experience with noSQL databases
  • Familiarity with machine learning methods
  • Knowledge of human or cancer genetics

Other information

Whilst the developments around COVID-19 continue to evolve, the Wellcome Genome Campus is closed for all but essential functions and facilities. 

People remain at the centre of everything that we do and the majority of our staff are now working remotely to ensure continuity of operations, making use of remote communication and collaboration tools.

Interviews will be taking place virtually and the successful candidate should expect to be fully supported through remote on-boarding and working from home until the Campus re-opens to all staff. This approach may vary for individuals located overseas and/or where a visa is required and starting will be based on a number of factors, we will be able to provide specialist advice to those affected candidates

Flexible Working:

We appreciate the importance of achieving a healthy work-life balance and support this with a number of benefits, including a flexible working policy for those who may wish to apply to amend their working pattern or arrangement. We welcome applications for this position that are looking for flexible working, such as flexible start and finish times, and equal consideration will be given to individuals regardless of their working preferences.

Application Process:

Please apply with your CV and a cover letter outlining your suitability for the role.

Closing date: 19th March 2021

Internal Applicants:

This role is suitable as a secondment opportunity, please discuss with your current line manager before submitting your application. 

About Us

The Wellcome Sanger Institute is a world leading genomics research centre. Our findings are used to improve health and to understand life on Earth.

Our benefits:

There’s an attractive benefits package on offer at the Wellcome Genome Campus. We appreciate the importance of achieving work-life balance and support this with a number of family and carer-friendly policies. Plus a flexible working policy for those who may wish to amend their working pattern or arrangement.
As well as the usual benefits you would expect, we go much further:

  • 25 days annual leave (extra 1 day to a maximum of 30 days for every year you work)
  • Auto-enrolment into a generous Group Defined Contribution Pension Scheme, with enhanced company contribution (for more information, see our Pensions page)
  • Up to 2 days annual paid volunteering leave
  • Up to 10 days paid Emergency Carers Leave per year
  • Family friendly environment including options for flexible and part-time working, an on-site Workplace Nursery salary Sacrifice Schemes for pre-school children and Summer holiday club
  • Life Assurance is accessible on day 1 for all 
  • Group Income Protection Scheme (if on a contract exceeding 12 months)
  • Enhanced maternity, parental and adoption leave
  • Access to substantial number of courses and training events onsite
  • Private Healthcare Scheme 
  • Eyecare and Dental payment plans
  • Concessions and discounts from our corporate perks site

Being part of the Wellcome Genome Campus you will be part of the beautiful working environment with an impressive range of benefits, services and facilities also including:

  • Free bus service to and from Campus, covering various routes around Cambridge, Saffron Walden and surrounding villages
  • A car-share initiative
  • Free parking
  • A number of on-site venues where you can meet, eat and socialise with colleagues
  • A thriving Sports and Social Club which provides members with subsidised access to a gym, tennis courts, sports hall, fitness classes and a vibrant social calendar of events

In 2020 we were awarded an Athena SWAN Silver Award. We will consider all individuals without discrimination and are committed to creating an inclusive environment for all employees, where everyone can thrive.

Apply now on-line

Rajat Singhhttps://bioinformaticsindia.com
Rajat Singh is the chief Author at Bioinformatics India, he has been writing for the past 3 years and has a special interest in SEO, Technology, Health, Life Sciences and gaming.

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