‘Scientific Breakthrough’: A protein folding mystery solved through AI after decades

‘Scientific Breakthrough’: A protein folding mystery solved through AI after decades

In a groundbreaking Deep Mind was able to detect how proteins fold up using the AI ‘AlphhaFold’ biennial critical evaluation of the protein structure prediction (CASP).

Artificial intelligence developed in the United Kingdom has solved a “protein folding problem for decades since mapping its 2D structures and distinguishing between various protein forms. Scientists have been unable for more than 50 years to decipher the genetics that could help improve therapies and medication efficacy.

However, on November 30, DeepMind in London revealed that its AlphaFold software was able to classify several protein types which could speed up research in drug design, disease management, and environmental sustainability.

In an opening case, DeepMind was able to detect how proteins fold through a detailed examination of many experimentally identified protein structures through the biennial Critical Audit of Protein Structure Projection(CASP). A total of around 200 million proteins are believed to exist. Researchers from the 14th CCW experiment (CASP14) solved the riddle in 1994 with the development of an attention-based neural network system which was learned to perceive structures using the new AI AlphaFold version.

170,000 protein structures ‘Trained’

“The AI system has developed strong physical predictions of the underlying structure of the protein and is able in a matter of days to determine highly accurate structures,” scientists recorded in a statement. AlphaFold has already been trained in 170,000 protein structures, providing an overall prediction of the accuracy score of 92.4 out of 100. In addition, AlphaFold could predict which aspects of a predicted protein structure are accurate. “This computer work marks an amazing breakthrough on the issue of protein folding, a major biology challenge of 50 years of age,” said President Venki Ramakrishnan of the Royal Society. “It is exciting to see how many ways biological research will fundamentally change,” he said.

‘Scientific Breakthrough’: A protein folding mystery solved through AI after decades

Rajat Singhhttps://bioinformaticsindia.com
Rajat Singh is the chief Author at Bioinformatics India, he has been writing for the past 3 years and has a special interest in SEO, Technology, Health, Life Sciences and gaming.

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