Precision Medicine: The concept, In this article, we discuss the approach in precise medicine and why it is better than current treatments and therapies. This is an overview of the concepts we are discussing today.
Overview of Precision Medicine
Precision medicine supports the idea that accurate treatments are tailored to “specific patients” and “a personalized plan” includes all of the specific characteristics of each patient. Some factors are just some of which must be taken into account in creating precise medicine treatments, the genome environment and patient lifestyle.
Coal miners will be treated differently from a Secretary or Janitor for lung cancer, as a coal miner’s environment consists of constant exposure to debris and other alien particulates susceptible to damage to the lungs whereas the secretary or janitor is less susceptible to such factors.
Precision Medicine: The concept
What is Precision Medicine?
The Precision Medicine graph shows the difference between medicine and current healthcare and the current medicine plans, allowing researchers and doctors to predict the efficacy of the medicines and treatments to ensure patients obtain best results from their medicines.
One drug is given to a group of patients without much knowledge of its effectiveness. The effect of this one size is very varied for all drug regimes. This drug results and improves your health for some patients. There may not be any changes for others and even for others this medicine may have a negative health effect.
This therapy is not as effective as it should be, as it does not provide everyone with an effective therapy solution. However, the approach to precision medicine is different.
It provides tailored health care plans to each individual by counting for different factors such as the genome their environment and their lifestyle by creating tailored plans for each individual and the overall effect for everyone is better and an improvement is almost always guaranteed.
There are a variety of factors that are required to increase precision medicine efficacy in the future.
- We need the genomes of affected patients to ensure that we have an available dataset for the majority of diseases.
- We need to control subjects or healthy people that are willing to participate in clinical trials and other research studies.
- Knowledge of various sickness paths is required to give us insight as to how somebody can contract a certain disease.
- Treatments to halt the sickness paths are needed so that other people in the same environment are not exposed to the same risk factors and are therefore not as in danger to contract a disease.
- We need to know the effect of treatments on certain factors to assess whether or not a specific treatment will control a certain aspect of someone’s lifestyle.
- We would also need methods to specify a sickness path for an individual based on their lifestyles and other factors.
- We need methods to determine an ideal treatment course.
Once a diagnosis has been established, the above factors must be identified for usage patterns. Clinical studies are the best way to get medical treatments out of the ground and there are certain similarities and differences between subjects.
For example, if all patients and a certain study are sensitive to the cyclo-jug mine for stomach cancer, the clinical trial is an effective cyclist test. The treatment could be induced by Foster. An additional example is that if a patient has HSV resistance approaching a gene, this patient population would be ideal for testing a job which increases the effect or protein folding and infected cells of that patient’s gene.
However not only similarities but also differences must be noticed in some clinical trials.
The healthy individuals or control subjects are of different ages and lifestyles. Not only can it be useful for testing certain characteristics of a therapy in the patients and the study at different stage of cancer, from one to four, but it is generically recommended that major discrepancies of this nature be kept to a low standard.
Three other differences that are worth mentioning are
Expressions differences in individual patients so far.
Current applications of precision medicine and its accessibility
It has been promoted by the dreams of the independent Community research community led by scientists and other investigators from different organizations, and AstraZeneca Sanger drug combination prediction Gene challenge. We will not go through all the details but only to show you that this challenge is one of the examples of an increased acceptance in NIH and the medical community of precision medicine.
The advancing advances in modern technology are part of the reason that precision medicine has become increasingly streamlined in healthcare. Most of these advances relate to genomic sequencing in the next generation, and genome sequence is one of the main factors for providing accuracy for all. This results in a monumental discovery of these new sequencing methods.
Non-sanger-based high-performance DNA sequencing technologies are called the next-generation sequencing and basically, they include the addition and detection of nucleotides in the DNA sequencing process in a single step that results in greater output and therefore minimize the need for fragmented cloning methods which are often used as Sanger genome sequences with this next-generation sequencing.
Scientists can sequence genomes more and more and at lower costs than ever before. This is to be reiterated in a diagram by the NIH National Institute for Human Genome Research. As can be seen, the first genome in 2001 was about $100 million in NIH sequence. It was very costly, but with time you see that the cost of sequencing a genomic has dropped dramatically, particularly around 2007-2008, and that the cost has not fallen sharply.
Companies like Illumina have allowed someone, in addition to private companies, to sequence the genome for under $100. One reason why genomic sequencing is becoming cheaper and more open to all is due to parties is because university laboratories and genome sequencing are participating, and in particular because of their participation, you have some very sophisticated genome sequencing technology in the market now.
Universities can significantly reduce costs and make genome sequencing more available to the public. The universities benefit not only from this but also from participating in state-of-the-art technology and exposing their students and faculty to this research. Precision medicine is the future of medicine and it provides better solutions for treating various conditions like cancer that currently do not have medicine and treatments today. Precision is the medical approach to medicine.
Computational biology is now an emerging field because much is done with the approach of precision medicine and intelligence. That is why we love biology competitions, and it’s something that we feel is really exciting to attend this course is just a way for me to help spread the word and involve people because we think it can affect a lot of lives.
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Precision Medicine: The concept